POS0517 ANTINUCLEAR ANTIBODIES IN GOUT: VICTIMS OF MODERN IMMUNOLOGY TECHNIQUES (A NEW VOMIT)

Background Non-rational prescription of tests in clinical practice may induce inefficient performances, misdiagnosis, and inappropriate consultations. Objectives We analyzed the results antinuclear antibodies (ANA) before first consultation to a rheumatology unit disease with commonly high diagnostic accuracy based on findings: gout. Methods In decade 2013-2022 ANA testing prior visit was added database, along general data variables related comorbid conditions characteristics made an analysis plausibly associated biennial changes through n rate prescription. Results From Jan 2013 Dec 2022, 504 patients gave written consent for inclusion, 66 (13.7%) women 415 men (86.3%), mean age at entrance cohort 73±14 65±14 years, respectively. had been prescribed 114 (23.7%) subjects, 28/66 (42.4%) 86/415 (p<0.001). No differences were observed other variables, such as age, time from onset, flares per year, tophi, or polyarticular distribution. The not consultation: arthralgia (24.4%), arthritis (21.7%) gout (25.3%). 31/114 (27.2%) positive (90% title <1/400), but only led new diagnosis (autoimmune hepatitis), two previous (Sjögren´s Syndrome Systemic Lupus). much higher (12/28, 42.9%) than (8/86, 22.1%). prescriptions showed significative increase during last (p= 0.007): 11.3% 2013-14, 21.4% 2015-16, 34.9% 1016-2017, 31.1% 2021-22. A valley SARS-COV2 pandemia 2019-2020 (19.7%). Conclusion rheumatic quite typical presentation gout, is unexpectedly high, highest women, despite old absence systemic clinic. elder our setting especially lead misdiagnosis management: VOMIT. Acknowledgements Cruces Rheumatology Association. Disclosure Interests Ana Maria Herrero-Beites: None declared, Cristina Vazquez-Puente: del Consuelo Modesto-Caballero: Fernando Perez-Ruiz Speakers bureau: Menarini, Astellas, Consultant of: Arthriti, Alnylam, LG, Protalix, Selecta.